Turning the PAGe on central control of the exercise pressor reflex in humans.
نویسندگان
چکیده
EXPERIMENTS IN BIOLOGICAL SCIENCE are often envisioned as ultimately providing rational approaches to problems confronting human health. Additionally, pragmatic solutions evoked by clinical problems often provoke new questions in basic science. Deep brain stimulation therapy in human patients with implanted electrodes (2, 4, 5) has provided an opportunity for evaluation of basic science predictions about the functional relevance of the periaqueductal gray (PAG) to the central circuits participating in the exercise pressor reflex.
منابع مشابه
Effects of lower-body negative pressure on sympathetic nerve responses to static exercise in humans. Microneurographic evidence against cardiac baroreflex modulation of the exercise pressor reflex.
Although previous studies in both animals and humans have suggested that cardiac baroreceptors modulate reflex sympathetic vasoconstriction during exercise, more recent studies in conscious animals have not supported this view. To further test this concept in humans, we measured sympathetic nerve discharge with intraneural microelectrodes while we used static handgrip to activate the exercise p...
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ورودعنوان ژورنال:
- Journal of applied physiology
دوره 110 4 شماره
صفحات -
تاریخ انتشار 2011